Catecholaminergic polymorphic ventricular tachycardia
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چکیده
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare genetic disease with an incidence of approximately 1:10,000 in European population and a very high mortality rate if left untreated, reaching 31% by the age of 30 years [1]. It is characterized by bidirectional or polymorphic ventricular tachycardias (VT) induced by an adrenergic triggering factor, such as emotional stress or physical activity, while some patients may also develop episodes of atrial fibrillation [1,2]. Stress-related syncope is the most common symptom in otherwise healthy children or adolescents, while sudden cardiac death due to degeneration of VT to ventricular fibrillation (VF) may also occur. Palpitations and dizziness during exercise represent more benign manifestations of the disorder [3].
منابع مشابه
Paradoxical Effect of Increased Diastolic Ca Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia
Catecholaminergic polymorphic ventricular tachycardia is a congenital arrhythmogenic disease linked to -adrenergic–induced ventricular arrhythmias that has a high mortality in children and young adults when untreated. As common features of the catecholaminergic polymorphic ventricular tachycardia phenotype, supraventricular arrhythmias have also been described in catecholaminergic polymorphic v...
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Background—Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is a genetic
متن کاملCatecholaminergic Polymorphic Ventricular Tachycardia.
Catecholaminergic polymorphic ventricular tachycardia is a rare cause of exercise-induced arrhythmia and sudden cardiac death in the pediatric patient. This arrhythmia is difficult to diagnose in the emergency department, given the range of presentations; thus, a familiarity with and high index of suspicion for this pathology are crucial. Furthermore, recognition of the characteristic electroca...
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Percutaneous renal sympathetic denervation in catecholaminergic polymorphic ventricular tachycardia
Catheter-based renal sympathetic denervation may be an alternative after unsuccessful conventional ablation attempts.
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تاریخ انتشار 2015